Niobium-catalyzed reduction of monofluoroarenes with LiAlH4

K Fuchibe, T Akiyama

Index: Fuchibe, Kohei; Akiyama, Takahiko Synlett, 2004 , # 7 p. 1282 - 1284

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Citation Number: 13

Abstract

The scope and limitations of this reaction are shown in Table [3] . [6] All of o-, m-, and p-fluorobiphenyls were reduced in the optimized system described in Table [3] to give biphenyl in good yields (entries 1, 6, 9). Not only simple fluorobiphenyls but also electron-rich methyl- or ethoxy-substituted fluorobiphenyls worked well to afford the corresponding products although prolonged time was required (entries 2, 3, 8). Chloride and bromide in fluorobiphenyl substrates were ...