Chemical Communications

Zn (ODf) 2: preparation and application in asymmetric alkynylation of aldehydes

Z Chen, W Xiong, B Jiang

Index: Chen, Zili; Xiong, Wennan; Jiang, Biao Chemical Communications, 2002 , # 18 p. 2098 - 2099

Full Text: HTML

Citation Number: 32

Abstract

A new Lewis acid, Zn (ODf) 2, was first prepared from commercially available 3, 3, 4, 4- tetrafluoro [1, 2] oxathietane 2, 2-dioxide in four steps with 56% yields and also was applied to catalyze highly enantioselective alkynylation of aldehydes in the presence of ligand (1S, 2S)-3-(tert-butyldimethylsilyloxyl)-2-N, N-dimethylamino-1-(p-nitrophenyl) propane-1-ol or ligand (−)-N-methylephedrine to afford the corresponding propargylic alcohols in high ...

Related Articles:

Effective activation of chiral BINOL/Ti (OiPr) 4 catalyst with phenolic additives for the enantioselective alkynylation of aldehydes

[Lu, Gui; Li, Xingshu; Chen, Gang; Chan, Wing Lai; Chan, Albert S. C. Tetrahedron Asymmetry, 2003 , vol. 14, # 4 p. 449 - 452]

Highly Enantiospecific Platinum-Catalyzed Cycloisomerizations: Synthesis of Enantioenriched Oxabicycloheptene Derivatives

[Newcomb, Eric T.; Ferreira, Eric M. Organic Letters, 2013 , vol. 15, # 7 p. 1772 - 1775]

More Articles...