Tetrahedron

Enzymatic resolution of norbornane-type esters

T Oberhauser, M Bodenteich, K Faber, G Penn…

Index: Oberhauser, Th.; Bodenteich, M.; Faber, K.; Penn, G.; Griengl, H. Tetrahedron, 1987 , vol. 43, # 17 p. 3931 - 3944

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Citation Number: 70

Abstract

Chiral norbornane-type alcohols of high optical purity were prepared via enzymatic resolution of their racemic esters using lipases from Candida cylindracea and Pseudomonas sp. This method presents a short and efficient access to a number of chiral building blocks on a molar scale for the synthesis of optically active cyclopentane systems.