Ring??opening nucleophilic alkylations by tertiary azetidines

VR Gaertner

Index: Gaertner,V.R. Journal of Heterocyclic Chemistry, 1969 , vol. 6, p. 273 - 277

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Citation Number: 7

Abstract

A-Alkylazetidines werc: cleaved by riucleophilic reagents under moderate conditions to give the corresponding ;l-substitrited-propylaInines. The additions were subject to acid catalysis and also proceeded slowly under alkaline SNZ conditions. ... , I I he effects of ring strain and substituents on the reactivity of small heterocycles are of continuing interest. Although the four-membered nitrogen heterocycles had generally heen considered to lack entirely the well- ...