Organic & biomolecular chemistry

Highly efficient synthesis of 2, 5-disubstituted pyrazines from (Z)-β-haloenol acetates

Z Chen, D Ye, G Xu, M Ye, L Liu

Index: Chen, Zhengwang; Ye, Dongnai; Xu, Guohai; Ye, Min; Liu, Liangxian Organic and Biomolecular Chemistry, 2013 , vol. 11, # 39 p. 6699 - 6702

Full Text: HTML

Citation Number: 3

Abstract

A highly efficient synthesis of a wide range of 2, 5-disubstituted pyrazines from (Z)-β- haloenol acetates is described. The reactions are conducted under convenient conditions and provide products with excellent regioselectivity in moderate to excellent yields with a broad substrate scope, including a variety of aromatic and aliphatic haloenol acetates.

Related Articles:

Microwave-assisted synthesis of α-hydroxy ketone and α-diketone and pyrazine derivatives from α-halo and α, α′-dibromo ketone

[Utsukihara, Takamitsu; Nakamura, Hiroaki; Watanabe, Masashige; Akira Horiuchi Tetrahedron Letters, 2006 , vol. 47, # 52 p. 9359 - 9364]

Syntheses and photophysical properties of some 5 (2)??aryl??2 (5)??(4??pyridyl) oxazoles and related oxadiazoles and furans

[Hall, J. Herbert; Chien, Joseph Yuming; Kauffman, Joel M.; Litak, Peter T.; Adams, Jeffrey K.; et al. Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1245 - 1273]

Syntheses and photophysical properties of some 5 (2)??aryl??2 (5)??(4??pyridyl) oxazoles and related oxadiazoles and furans

[Hall, J. Herbert; Chien, Joseph Yuming; Kauffman, Joel M.; Litak, Peter T.; Adams, Jeffrey K.; et al. Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1245 - 1273]

Syntheses and photophysical properties of some 5 (2)??aryl??2 (5)??(4??pyridyl) oxazoles and related oxadiazoles and furans

[Hall, J. Herbert; Chien, Joseph Yuming; Kauffman, Joel M.; Litak, Peter T.; Adams, Jeffrey K.; et al. Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1245 - 1273]

More Articles...