Ni (II)-catalyzed cross-coupling between polyfunctional arylzinc derivatives and primary alkyl iodides

R Giovannini, P Knochel

Index: Giovannini; Knochel Journal of the American Chemical Society, 1998 , vol. 120, # 43 p. 11186 - 11187

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Citation Number: 113

Abstract

A cross-coupling reaction between organometallics and alkyl halides is an important method for the formation of new carboncarbon bonds. Many biologically active molecules contain aromatic rings so that the performance of an efficient crosscoupling between C sp2- hybridized organometallics and alkyl halides is needed. Although the palladium-or nickel- catalyzed cross-coupling between alkyl organometallics RM (M) B, Al, Zn, Mg, etc.) and ...

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