Synthesis and biological evaluation of substituted (thieno [2, 3-d] pyrimidin-4-ylthio) carboxylic acids as inhibitors of human protein kinase CK2

AG Golub, VG Bdzhola, NV Briukhovetska…

Index: European Journal of Medicinal Chemistry, , vol. 46, # 3 p. 870 - 876

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Citation Number: 39

Abstract

... European Journal of Medicinal Chemistry. ... Yield 86%; mp 138–139 °C; 1 H NMR (400 MHz, DMSO-d 6 ): δ: 1.42 (3H, t, CH 3 ), 2.56 (2H, t, CH 2 ), 3.29 (2H, t, CH 2 ), 4.08 (2H, q, CH 2 ), 6.91 (2H, d, J = 8.5, 4-CH 3 CH 2 OC 6 H 4 ), 7.26 (2H, d, J = 8.5, 4-CH 3 CH 2 OC 6 H 4 ...

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