1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1, 3-dihydroimidazol-2-one: A selective high-affinity antagonist for the human dopamine D4 receptor with excellent …

RW Carling, KW Moore, CR Moyes…

Index: Journal of Medicinal Chemistry, , vol. 42, # 14 p. 2706 - 2715

Full Text: HTML

Citation Number: 59

Abstract

... Journal of Medicinal ... Departments of Medicinal Chemistry, Biochemistry, and Pharmacology, Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre ... it is widely accepted that brain dopamine receptors are the primary targets for medical treatment. ...

Related Articles:

Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 4: synthesis and structure–Activity relationships for 1-[N-(Methyl)-N-(phenylsulfonyl) amino]-2-( …

[Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 18 p. 2475 - 2479]

An Improved Synthesis of Butyl 4-[(4-Amino-5-chloro-2-methoxybenzoyl) amino]-1-piperidineacetate (AU-224).

[Chemical and Pharmaceutical Bulletin, , vol. 49, # 6 p. 788 - 790]

Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 4: synthesis and structure–Activity relationships for 1-[N-(Methyl)-N-(phenylsulfonyl) amino]-2-( …

[Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 18 p. 2475 - 2479]

More Articles...