Microwave-assisted synthesis of the antihyperglycemic drug rosiglitazone

SL Gaonkar, H Shimizu

Index: Gaonkar, Santosh L.; Shimizu, Hiroki Tetrahedron, 2010 , vol. 66, # 18 p. 3314 - 3317

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Citation Number: 31

Abstract

We developed a simple, rapid, high yielding, and environmentally benign microwave assisted total synthesis of rosiglitazone, an antihyperglycemic agent for diabetes mellitus Type II. We used microwave heating successfully to improve reactions in four of six steps ...