Influence of the adamantyl moiety on the activity of biphenylacrylohydroxamic acid-based HDAC inhibitors

R Cincinelli, L Musso, G Giannini, V Zuco…

Index: European Journal of Medicinal Chemistry, , vol. 79, p. 251 - 259

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Citation Number: 7

Abstract

... European Journal of Medicinal Chemistry. ... [12], followed by a large number of studies on compounds for diverse medicinal applications [3 ... i) Bis(pinacolato)diboron, PdCl 2 (dppf), KOAc, dioxane, 100 °C, 13 h, then 8, 2 M Na 2 CO 3 , PdCl 2 (dppf), reflux, 4 h, 86%; j) PTSA, MeOH ...

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