Russian journal of general chemistry

Reaction of antipyrine with Schiff bases

NG Kozlov, LI Basalaeva

Index: Kozlov; Basalaeva Russian Journal of General Chemistry, 2006 ,  vol. 76,  # 2  p. 302 - 306

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Citation Number: 1

Abstract

1-Phenyl-2,3-dimethylpyrazol-5-one (antipyrine) is an important pyrazolone derivative and is widely used for a long time in medicine as antipyretic, analgetic, and sedative [1, 2]. At present it is one of the main agents for treatment of diseases characterized by cyclic progress and pronounced temperature reaction [3]. The chemical structure of 1-phenyl-2,3-dimethyl- pyrazol-5-one suggests that one of possible routes to its new derivatives is the reaction with compounds ...