Chemistry Letters

Homoaldol and Aldol Reactions from Common Enolates and Oxiranes: Reaction of Reductively Generated Chromium Enolates through Cationic Rearrangement.

…, K Sakata, X Maimaiti, J Ueno, H Nishikori, A Hosomi

Index: Hojo, Makoto; Sakata, Kyosuke; Maimaiti, Xiamuxikamaer; Ueno, Junya; Nishikori, Hisashi; Hosomi, Akira Chemistry Letters, 2002 , # 2 p. 142 - 143

Full Text: HTML

Citation Number: 8

Abstract

Enolates are a fundamental species for organic synthesis, and the aldol reaction is a representative reaction of enolates, where both the carbon-carbon bond formation and the creation of a functional hydroxy group for the further synthetic manipulations are achieved in a single event.1 As for the homologue, homoaldol reaction, synthetic equivalents of homoenolates are usually used as nucleophiles toward carbonyl compounds.2 We recently found that -halo carbonyl ...