Evaluation of 1, 3-diaxial steric hindrance to proton abstraction alpha to carbonyl groups

…, JM Dostal, JD Trometer, TA Spencer

Index: Gula, M. J.; Vitale, D. E.; Dostal, J. M.; Trometer, J. D.; Spencer, T. A. Journal of the American Chemical Society, 1988 ,  vol. 110,  # 13  p. 4400 - 4405

Full Text: HTML

Citation Number: 10

Abstract

Abstract: An assessment of the magnitude of steric hindrance by axial substituents to abstraction of syn-axial protons alpha to carbonyl groups in trans-fused decalones has been made by a comparison of the rates of reactions of beta acetoxy ketones 7, 4, 8, and 9 to ...