1-Palmitoyl-2-thiopalmitoyl phosphatidylcholine, a highly specific chromogenic substrate of phosphol ipase A2

C Balet, KA Clingman, J Hajdu

Index: Bhatia, Suresh K.; Hajdu, Joseph Tetrahedron Letters, 1987 ,  vol. 28,  # 16  p. 1729 - 1732

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Citation Number: 19

Abstract

Abstract 1-Palmitoyl-2-thiopalmitoyl phosphatidylcholine (2-thioPC), a structurally modified phospholipid analog is specifically hydrolyzed by phospholipase A 2 to liberate 2- thiolysophosphatidylcholine and palmitic acid. The sulfhydryl group of the product is readily