Tetrahedron

A novel thiochromone-type photolabile protecting group for carbonyl compounds

…, R Kozaki, S Kitani, Y Gosho, H Tanimoto, Y Nishiyama…

Index: Sugiura, Ryo; Kozaki, Rikio; Kitani, Satoru; Gosho, Yoshinori; Tanimoto, Hiroki; Nishiyama, Yasuhiro; Morimoto, Tsumoru; Kakiuchi, Kiyomi Tetrahedron, 2013 ,  vol. 69,  # 19  p. 3984 - 3990

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Citation Number: 8

Abstract

A novel photolabile protecting group, thiochromone S, S-dioxide, possessing the 1, 2-diol group for protection of ketones and aldehydes is described. Photodeprotection of the successfully protected carbonyl derivatives proceeded smoothly under photoirradiation filtered through Pyrex glass (> 280 nm) using an ultrahigh-pressure mercury lamp to recover the corresponding carbonyl compounds and the starting protecting group.