A Practical Synthesis of a cis-4, 5-Bis (4-chlorophenyl) imidazoline Intermediate for Nutlin Analogues

L Shu, P Wang, W Liu, C Gu

Index: Organic Process Research and Development, , vol. 16, # 11 p. 1866 - 1869

Full Text: HTML

Citation Number: 5

Abstract

... 2 was prepared in 51% yield from p-chlorobenzaldehyde using an optimized process based on ... quantity of compound 5 was prepared by contract suppliers following the procedure described below. ... After 5 min of stirring, the organic layer was separated, washed with water (200 ...