Doping in sport: 3. Metabolic conversion of oral norethisterone to urinary 19-norandrosterone

…, DA Cowan, VHT James, JCY Lau, AT Kicman

Index: Walker, Christopher J.; Cowan, David A.; James, Vivian H.T.; Lau, Joanne C.Y.; Kicman, Andrew T. Steroids, 2009 , vol. 74, # 3 p. 335 - 340

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Citation Number: 6

Abstract

The detection of 19 norandrosterone (19-NA) in a competitor's urine sample is taken as prima facie evidence of administration of nandrolone or other 19-norsteroid but a potential problem is that administration of norethisterone, a progestogen used for menstrual disorders and for hormonal contraception, also results in the excretion of 19-NA that can exceed the laboratory reporting threshold of 2ng/mL. The contribution of norethisterone to urinary 19- ...