Synthesis and biological characteristics of the Technetium??99m triamide derivatives of mercaptoacetyltriglycine (MAG3)

…, P Adriaens, AM Verbruggen

Index: Okarvi; Verbeke; Adriaens; Verbruggen Journal of Labelled Compounds and Radiopharmaceuticals, 2002 , vol. 45, # 2 p. 115 - 137

Full Text: HTML

Citation Number: 7

Abstract

Abstract A number of MAG 3-derivatives, containing the three-amide functions modified by inverting the sequence–CO–NH–to–NH–CO–in the first-and/or second-amide functions, have been labelled with 99m Tc in order to study the renal characteristics of the resulting MAG 3-derivatives versus the reference 99m Tc-MAG 3. The 99m Tc-MAG 3-derivatives displayed HPLC-profiles similar to that of 99m Tc-MAG 3. Furthermore, in mice they ...

Related Articles:

Reactions of Mustard-type Vesicants with α-Amino Acids1

[du Vigneaud et al. Journal of the American Chemical Society, 1948 , vol. 70, p. 1620,1621]

Building units for N-backbone cyclic peptides. Part 4. 1 Synthesis of protected N α-functionalized alkyl amino acids by reductive alkylation of natural amino acids

[Bitan, Gal; Muller, Dan; Kasher, Ron; Gluhov, Evgenia V.; Gilon, Chaim Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 10 p. 1501 - 1510]

Building units for N-backbone cyclic peptides. 2. Synthesis of protected N-(ω-thioalkylene) amino acids and their incorporation into dipeptide units

[Bilan, Gal; Gilon, Chaim Tetrahedron, 1995 , vol. 51, # 38 p. 10513 - 10522]

More Articles...