The Journal of Organic Chemistry

Spiroheterocycles from the reaction of nitrile oxides with 3-methylenephthalimidines

RK Howe, BR Shelton

Index: Howe, Robert K.; Shelton, Becky R. Journal of Organic Chemistry, 1990 , vol. 55, # 15 p. 4603 - 4607

Full Text: HTML

Citation Number: 113

Abstract

In explorations of syntheses and chemistry of spiroheterocycles, we found that reaction of aromatic nitrile oxides with 3-methylenephthalimidines 8 produced spiroheterocycles 9. When N-benzyl-3-methylenephthdimidine (8c) was employed, oximes 10 and 11 were formed in addition to the spiroheterocycles. Solvent effects on the reaction rates and on product ratios indicate that the product mixtures result from competition between a 1, 3- ...

Related Articles:

Synthesis of 3-methyleneisoindolin-1-ones via palladium-catalyzed C–Cl bond cleavage and cyclocarbonylation of ortho-chloro ketimines

[Ju, Jia; Qi, Chuanmei; Zheng, Liyao; Hua, Ruimao Tetrahedron Letters, 2013 , vol. 54, # 38 p. 5159 - 5161]

Palladium-Catalysed Heteroannulation with Terminal Alkynes: a Highly Regio-and Stereoselective Synthesis of (Z)-3-Aryl (alkyl) idene Isoindolin-1-ones

[Kundu, Nitya G.; Khan, M. Wahab Tetrahedron, 2000 , vol. 56, # 27 p. 4777 - 4792]

Palladium-Catalysed Heteroannulation with Terminal Alkynes: a Highly Regio-and Stereoselective Synthesis of (Z)-3-Aryl (alkyl) idene Isoindolin-1-ones

[Kundu, Nitya G.; Khan, M. Wahab Tetrahedron, 2000 , vol. 56, # 27 p. 4777 - 4792]

Palladium-Catalysed Heteroannulation with Terminal Alkynes: a Highly Regio-and Stereoselective Synthesis of (Z)-3-Aryl (alkyl) idene Isoindolin-1-ones

[Kundu, Nitya G.; Khan, M. Wahab Tetrahedron, 2000 , vol. 56, # 27 p. 4777 - 4792]

Palladium-Catalysed Heteroannulation with Terminal Alkynes: a Highly Regio-and Stereoselective Synthesis of (Z)-3-Aryl (alkyl) idene Isoindolin-1-ones

[Kundu, Nitya G.; Khan, M. Wahab Tetrahedron, 2000 , vol. 56, # 27 p. 4777 - 4792]

More Articles...