SN1??Type Reactions in the Presence of Water: Indium (III)??Promoted Highly Enantioselective Organocatalytic Propargylation of Aldehydes

R Sinisi, MV Vita, A Gualandi, E Emer…

Index: Sinisi, Riccardo; Vita, Maria Victoria; Gualandi, Andrea; Emer, Enrico; Cozzi, Pier Giorgio Chemistry - A European Journal, 2011 , vol. 17, # 27 p. 7404 - 7408

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Citation Number: 47

Abstract

Organocatalysis has received considerable attention in the past 10 years [1] and is becoming an exciting area of research, particularly as organocatalytic transformations are now being considered in the design of syntheses of complex natural products [2] and drugs.[3] Most of the organocatalytic reactions involve two basic activation routes: enamine catalysis [4] and iminium catalysis.[5] More recently, the combination of oxidants in the ...