The discovery of UK-369003, a novel PDE5 inhibitor with the potential for oral bioavailability and dose-proportional pharmacokinetics

DJ Rawson, S Ballard, C Barber, L Barker…

Index: Bioorganic and Medicinal Chemistry, , vol. 20, # 1 p. 498 - 509

Full Text: HTML

Citation Number: 13

Abstract

... Bioorganic & Medicinal Chemistry. ... a Worldwide Medicinal Chemistry, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK; b Department of Pharmacokinetics, Dynamics and Metabolism, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK; ... 2. Chemistry. UK-343664 (2) (Fig. ...