Direct conversion of pinacol arylboronic esters to aryl triolborates

GQ Li, S Kiyomura, Y Yamamoto, N Miyaura

Index: Li, Gao-Qiang; Kiyomura, Shunsuke; Yamamoto, Yasunori; Miyaura, Norio Chemistry Letters, 2011 , vol. 40, # 7 p. 702 - 704

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Citation Number: 11

Abstract

Conversion of pinacol arylboronic esters 3 to aryl triolborates 5 via transesterification with 1, 1, 1-tris (hydroxymethyl) ethane (4) was established with the advantages of tolerance to various functional groups. Transesterification was carried out at 30–60° C in dioxane in the presence of MOH (M= Na and K) and H 2 O. High yields were achieved for stable aryl triolborates 5.