Heterocycles

Synthesis of 4-(1, 4-diaryl-2H-cyclopent [d] pyridazin-2-yl)-benzenesulfonamides

M Blankenbuehler, S Parkin

Index: Blankenbuehler, Mark; Parkin, Sean Heterocycles, 2002 , vol. 57, # 12 p. 2383 - 2391

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Citation Number: 6

Abstract

Abstract-The condensation of cyclopentadienyl-derived γ-diketones and arylhydrazines was utilized to synthesize 4-(1, 4-diphenyl-2H-cyclopent [d]-pyridazin-2-yl) benzenesulfonamide and 4-(1, 4-di-(4-methylphenyl)-2H-cyclopent [d] pyridazin-2-yl) benzenesulfonamide in better than 80% yield. The crystal structures of the precursor hydroxyfulvene,{(5Z)-5-[hydroxy (4-methylphenyl)-methylene] cyclopenta-1, 3-dien-1-yl}(4-methylphenyl) methanone, and ...