Carcinogen chemistry. 4.(Haloalkyl) oxonium and (haloalkyl) carboxonium ions. Preparation, nuclear magnetic resonance structural study, and alkylating ability

…, S Yu, G Liang, GD Matseescu, MR Bruce…

Index: Olah, George A.; Yu, Simon; Liang, Gao; Matseescu, Gheorghe D.; Bruce, Mark R.; et al. Journal of Organic Chemistry, 1981 , vol. 46, # 3 p. 571 - 577

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Citation Number: 14

Abstract

For exploration of the in vitro formation of the potential carcinogenic alkylating agents and particularly the reactive ionic intermediates derived from formaldehyde-hydrogen halides and haloalky ethers, their protolytic ionization under stable-ion conditions in low- nucleophilicity solutions was studied. The preparation, a NMR spectroscopic structural study, and the alkylating ability of a series of (haloalky1) oxonium and (haloalky1)- ...