Synthesis of 6-substituted 2-(N-acetylamino) pyridines and 2-aminopyridines by cyclization of 5-oximinoalkanenitriles

RJ Vijn, HJ Arts, PJ Maas…

Index: Journal of Organic Chemistry, , vol. 58, # 4 p. 887 - 891

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Citation Number: 29

Abstract

... (1% Schaefer, F. C. In The Chemistry ofthe Cyano ... at such a rate that the temperature remains below 20 "C. After addition of NaOH, the mixture is stirred for 16 h. The organic phase is ... 1H NMR (200 MHz): 9.5 (br 8, 1 H, OH), 2.42 (t, J = 6, 2 H), and 2.35 (t, J = 6, 2 H) (CHzCN, N ...

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