Preparation of alkyl chlorides, acid chlorides, and amides using polymer-supported phosphines and carbon tetrachloride: mechanism of these reactions

…, BJ Hunt, E Khoshdel, G Richardson

Index: Harrison, Charles R.; Hodge, Philip; Hunt, Barry J.; Khoshdel, Ezzatollah; Richardson, Graham Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3721 - 3728

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Citation Number: 71

Abstract

Alcohols and thiols were converted into alkyl chlorides, carboxylic acids were converted into acid chlorides, and mixtures of carboxylic acids and amines were converted into amides by reaction with carbon tetrachloride and 1% cross-linked polystyrenes containing phosphine residues. Some of these conversions were also effected by using a linear polymer containing phosphine residues. The reactions proceed in high yield, and isolation of the ...