Tetrahedron Letters

Ru (III)-catalyzed oxidative reaction in ionic liquid: an efficient and practical route to 2-substituted benzothiazoles and their hybrids with pyrimidine nucleoside

X Fan, Y Wang, Y He, X Zhang, J Wang

Index: Fan, Xuesen; Wang, Yangyang; He, Yan; Zhang, Xinying; Wang, Jianji Tetrahedron Letters, 2010 , vol. 51, # 27 p. 3493 - 3496

Full Text: HTML

Citation Number: 21

Abstract

An efficient, practical and environmentally benign synthesis of 2-substituted benzothiazoles was developed through RuCl3-catalyzed oxidative condensation of 2-aminothiophenol with aldehyde in ionic liquid by using air as the oxidant. With this procedure, a series of 2- substituted benzothiazoles and benzothiazole/pyrimidine nucleoside hybrids with antimicrobial activities were efficiently prepared from easily accessible starting materials.

Related Articles:

Synthesis of Benzothiazoles through Copper??Catalyzed One??Pot Three??Component Reactions with Use of Sodium Hydrosulfide as a Sulfur Surrogate

[Park, Namjin; Heo, Yumi; Kumar, Manian Rajesh; Kim, Yong; Song, Kwang Ho; Lee, Sunwoo European Journal of Organic Chemistry, 2012 , # 10 p. 1984 - 1993]

Eco-friendly atom-economical synthesis of 2-substituted-benzo [d] thiazoles and 2-substituted-benzo [d] oxazoles using 2-acylpyridazin-3 (2H)-ones

[Sung, Gi Hyeon; Lee, In-Hye; Kim, Bo Ram; Shin, Dong-Soo; Kim, Jeum-Jong; Lee, Sang-Gyeong; Yoon, Yong-Jin Tetrahedron, 2013 , vol. 69, # 17 p. 3530 - 3535]

Synthesis, anticancer activity and docking of some substituted benzothiazoles as tyrosine kinase inhibitors

[Bhuva, Hemal A.; Kini, Suvarna G. Journal of Molecular Graphics and Modelling, 2010 , vol. 29, # 1 p. 32 - 37]

Synthesis, anticancer activity and docking of some substituted benzothiazoles as tyrosine kinase inhibitors

[Bhuva, Hemal A.; Kini, Suvarna G. Journal of Molecular Graphics and Modelling, 2010 , vol. 29, # 1 p. 32 - 37]

Synthesis, anticancer activity and docking of some substituted benzothiazoles as tyrosine kinase inhibitors

[Bhuva, Hemal A.; Kini, Suvarna G. Journal of Molecular Graphics and Modelling, 2010 , vol. 29, # 1 p. 32 - 37]

More Articles...