Reactions of 4-chloro-1-nitrobenzene with o-substituted phenylacetonitriles; Synthesis of 8-chloro-1-methyl (and methylthiomethyl)-6-(2-substituted phenyl)-4H-s- …

…, J Holubek, M Ryska, I Koruna, E Svátek…

Index: Vejdelek, Zdenek; Holubek, Jiri; Ryska, Miroslav; Koruna, Ivan; Svatek, Emil; et.al. Collection of Czechoslovak Chemical Communications, 1987 , vol. 52, # 10 p. 2545 - 2563

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Citation Number: 7

Abstract

Abstract Reactions of 4-chloro-1-nitrobenzene with 2-methyl-, 2-methoxy-and 2-(methylthio) phenylacetonitrile in methanolic potassium hydroxide gave mixtures from which the expected 3-aryl-5-chloro-2, 1-benzisoxazoles Ia-c were isolated in addition to the 2H- indoles IIIa and IIIc and acridines VIII and IX. The 2, 1-benzisoxazoles were reduced to the 2- aminobenzophenones XIIa-c which were transformed via the phthalimidoacetamido ...

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