Chemistry–A European Journal

Palladium??Catalyzed Carbonylation Reaction of Aryl Bromides with 2??Hydroxyacetophenones to Form Flavones

XF Wu, H Neumann, M Beller

Index: Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias Chemistry - A European Journal, 2012 , vol. 18, # 40 p. 12595 - 12598

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Abstract

Flavones are an important class of natural products with a wide range of biological activities, such as anti-cancer, antiinflammatory and antioxidant activities,[2] and pharmaceutical applications (Scheme 1).[1] Because of their importance, numerous procedures have been reported for their preparation. One of the classical methodologies is the Baker– Venkataraman rearrangement, but the need for acyl chloride substrates and relatively ...

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