Cu-Mediated Chemoselective Trifluoromethylation of Benzyl Bromides Using Shelf-Stable Electrophilic Trifluoromethylating Reagents

H Kawai, T Furukawa, Y Nomura, E Tokunaga…

Index: Yarovenko; Vasileva Zhurnal Obshchei Khimii, 1958 , vol. 28, p. 2502

Full Text: HTML

Citation Number: 82

Abstract

... Volume: Page: Digital Object Identifier (DOI). ... For instance, o-, m-, and p-nitrobenzyl bromides 1a–c and dinitro-substituted benzyl bromide 1d were nicely converted into trifluoromethyl compounds 2a–d in 56–81% yields. ...

Related Articles:

Aromatic substitution. 53. Electrophilic nitration, halogenation, acylation, and alkylation of (. alpha.,. alpha.,. alpha.-trifluoromethoxy) benzene

[Olah,G.A.; Yamato,T.; Hashimoto,T. Journal of the American Chemical Society, 1987 , vol. 109, p. 3708]

Aromatic substitution. 53. Electrophilic nitration, halogenation, acylation, and alkylation of (. alpha.,. alpha.,. alpha.-trifluoromethoxy) benzene

[Olah,G.A.; Yamato,T.; Hashimoto,T. Journal of the American Chemical Society, 1987 , vol. 109, p. 3708]

Fluorination of aromatic derivatives with fluoroxytrifluoromethane and bis (fluoroxy) difluoromethane

[Fifolt, Michael J.; Olczak, Raymond T.; Mundhenke, Rudolph F. Journal of Organic Chemistry, 1985 , vol. 50, # 23 p. 4576 - 4582]

Versatile application of trifluoromethyl triflate

[Kolomeitsev, Alexander A.; Vorobyev, Mikhail; Gillandt, Hartmut Tetrahedron Letters, 2008 , vol. 49, # 3 p. 449 - 454]

Fluorination of aromatic derivatives with fluoroxytrifluoromethane and bis (fluoroxy) difluoromethane

[Fifolt, Michael J.; Olczak, Raymond T.; Mundhenke, Rudolph F. Journal of Organic Chemistry, 1985 , vol. 50, # 23 p. 4576 - 4582]

More Articles...