Tetrahedron letters

Investigation of stereoselectivities in the coupling reactions of 1-O-methyl-3, 5-di-Op-toluoyl-2-deoxyribofuranoside with purines and pyrimidines

S Janardhanam, KP Nambiar

Index: Janardhanam, Selvasekaran; Nambiar, Krishnan P. Tetrahedron Letters, 1994 , vol. 35, # 22 p. 3657 - 3660

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Citation Number: 13

Abstract

Abstract Stereoselectivities in the coupling reaction between 1-O-methyl-3, 5-di-Op-toluoyl-2- deoxyribofuranoside and suitably protected purine and pyrimidine derivatives have been examined in acetonitrile with varying equivalents of SnCl 4. The best result in α-nucleoside formation was obtained when the coupling reaction was carried out in the presence of ten equivalents of SnCl 4.

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