A Simple Procedure for Synthesis of Roxindole, a Dopamine D2??Receptor Agonist

F Csende

Index: Csende, Ferenc Archiv der Pharmazie (Weinheim, Germany), 2001 , vol. 334, # 7 p. 253 - 254

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Abstract

Abstract A modified convenient and high yielding synthetic route for the preparation of the dopamine agonist roxindole 1 is described. The key step in our method is the phase-transfer catalyzed reaction of γ-butyrolactone with 5-methoxyindole which results in the indolyl-