Cryptolepine analogues containing basic aminoalkyl side-chains at C-11: synthesis, antiplasmodial activity, and cytotoxicity

J Lavrado, A Paulo, J Gut, PJ Rosenthal…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 4 p. 1378 - 1381

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Citation Number: 40

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 1) is the major alkaloid from the roots of the west African climbing shrub Cryptolepis sanguinolenta, an herbal drug used in traditional medicine for the treatment of malaria. 4 and 5 Cryptolepine and its hydrochloride, 3 (Fig. ...