A Caged Retinoic Acid for One??and Two??Photon Excitation in Zebrafish Embryos

P Neveu, I Aujard, C Benbrahim…

Index: Neveu, Pierre; Aujard, Isabelle; Benbrahim, Chouaha; Le Saux, Thomas; Allemand, Jean-Francois; Vriz, Sophie; Bensimon, David; Jullien, Ludovic Angewandte Chemie - International Edition, 2008 , vol. 47, # 20 p. 3744 - 3746

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Citation Number: 61

Abstract

The embryogenesis of a multicellular organism relies on the spatiotemporal control of the concentrations of signaling molecules and the way cells respond to them.[1] One of these, retinoic acid (RA), plays a key role in patterning the body axis and in the formation of many organs.[2] RA concentration is finely regulated both spatially and temporally and its alteration results in developmental defects. An ability to artificially tune the RA ...

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