Tetrahedron letters

Cu (OTf) 2 or Et 3 N-catalyzed three-component condensation of aldehydes, amines and cyanides: a high yielding synthesis of α-aminonitriles

AS Paraskar, A Sudalai

Index: Paraskar, Abhimanyu S.; Sudalai, Arumugam Tetrahedron Letters, 2006 , vol. 47, # 32 p. 5759 - 5762

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Citation Number: 65

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Copper(II) triflate or Et 3 N have been found to catalyze, under ambient conditions, the addition of a cyanide anion, such as trimethylsilyl cyanide or acetone cyanohydrin, onto in situ generated imines, furnishing α-aminonitriles in excellent yields. ... Copper(II) triflate or Et 3 N have ...

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