Exceptionally easy isomerization of acetylenic alcohols with potassium 3-aminopropylamide. A new, high yield synthesis of functionally differentiated αω-difunctional …

CA Brown, A Yamashita

Index: Brown,C.A.; Yamashita,A. Journal of the Chemical Society, Chemical Communications, 1976 , p. 959 - 960

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Citation Number: 19

Abstract

Potassium 3-aminopropylamide, readily prepared in situ from KH and 3-aminopropylamine, effects rapid, multipositional isomerization of the triple bond in prop-2-ynylic and other acetylenic alcohols to the chain terminus remote from the hydroxy function, within minutes at 0–20° C.