Piperidine carboxylic acid derivatives of 10H-pyrazino [2, 3-b][1, 4] benzothiazine as orally-active adhesion molecule inhibitors

T Kaneko, RSJ Clark, N Ohi, F Ozaki…

Index: Itoh; Kori; Inada; Nishikawa; Kawamatsu; Sugihara Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 9 p. 3747 - 3761

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Citation Number: 7

Abstract

... Chemistry We first prepared the right moieties of the compounds 2. The piperidine carboxylates 4a—c are either commercially ... 2004 Pharmaceutical Society of ... resonance (1H-NMR) spectra were recorded on a Varian Unity 400 (400 MHz) spectrometer, and chemical shifts are ...