Design, synthesis, and activity of 2-imidazol-1-ylpyrimidine derived inducible nitric oxide synthase dimerization inhibitors
DD Davey, M Adler, D Arnaiz, K Eagen…
Index: Journal of Medicinal Chemistry, , vol. 50, # 6 p. 1146 - 1157
Full Text: HTML
Citation Number: 53
Abstract
... Journal of Medicinal Chemistry. ... and ecNOS isoforms. The potential therapeutic benefit of an iNOS inhibitor has prompted a major effort in the pharmaceutical industry to discover a potent, selective iNOS inhibitor. 1-3. ...
Related Articles:
[Davey, David D.; Adler, Marc; Arnaiz, Damian; Eagen, Keith; Erickson, Shawn; Guilford, William; Kenrick, Margaret; Morrissey, Michael M.; Ohlmeyer, Mike; Pan, Gonghua; Paradkar, Vidyadhar M.; Parkinson, John; Polokoff, Mark; Saionz, Kurt; Santos, Cecile; Subramanyam, Babu; Vergona, Ron; Wei, Robert G.; Whitlow, Marc; Ye, Bin; Zhao, Zuchun; Devlin, James J.; Phillips, Gary Journal of Medicinal Chemistry, 2007 , vol. 50, # 6 p. 1146 - 1157]