Synthesis of Triple-Bond-Containing 1-Hydroxy-1, 1-bisphosphonic Acid Derivatives To Be Used as Precursors in “Click” Chemistry: Two Examples
PA Turhanen
Index: Alanne, Aino-Liisa; Ylisirnioe, Markku; Turhanen, Petri; Peraeniemi, Sirpa; Vepsaelaeinen, Jouko; Hyvoenen, Helena; Lahtinen, Manu; Kolehmainen, Erkki Molecules, 2012 , vol. 17, # 9 p. 10928 - 10945,18
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Citation Number: 4
Abstract
The synthesis of novel (ω-alkynyl-1-hydroxy-1, 1-diyl) bisphosphonic acid tetramethyl esters (1a–c), their P, P′-dimethyl esters (2a–c), and two trimethyl ester derivatives (3a and 3b) is reported. The prepared compounds can be attached to many kinds of molecules containing
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