Improved Synthesis of Thromboxane A2 Receptor Antagonists With a Dibenzoxepin Ring System

T Sugaya, N Kato, A Sakaguchi, S Tomioka

Index: Synthesis, , # 10 p. 1257 - 1262

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Citation Number: 6

Abstract

... The formylmethylidene deriva- tive 6 was synthesized by a Wittig reaction followed by a Vilsmeier ... SYNTHESIS 1261 Methyl 11-Oxo-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate (2): To a ... Dimethyl-2-nitroformanilide (14): To chilled HCOZH (50 mL) was added Ac2O (10 mL), the ...