Arylalkyl Ketones, Benzophenones, Desoxybenzoins and Chalcones Inhibit TNF?螃? Induced Expression of ICAM??1: Structure??Activity Analysis
S Kumar, L Reddy, C Shekhar, Y Kumar…
Index: Kumar, Sarvesh; Reddy L, Chandra Shekhar; Kumar, Yogesh; Kumar, Amit; Singh, Brajendra K.; Kumar, Vineet; Malhotra, Shashwat; Pandey, Mukesh K.; Jain, Rajni; Thimmulappa, Rajesh; Sharma, Sunil K.; Prasad, Ashok K.; Biswal, Shyam; Van Der Eycken, Erik; Depass, Anthony L.; Malhotra, Sanjay V.; Ghosh, Balaram; Parmar, Virinder S. Archiv der Pharmazie, 2012 , vol. 345, # 5 p. 368 - 377
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Citation Number: 6
Abstract
Abstract The interaction between leukocytes and the vascular endothelial cells (EC) via cellular adhesion molecules plays an important role in the pathogenesis of various inflammatory and autoimmune diseases. Small molecules that block these interactions have been targeted as potential therapeutic agents against acute and chronic inflammatory diseases. In an effort to identify potent intercellular cell adhesion molecule-1 (ICAM-1) ...
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