Chemical Communications

Synthesis, spectroscopic characterization and chemical reactions of stable o-QM on solid phase

R Zanaletti, M Freccero

Index: Zanaletti, Riccardo; Freccero, Mauro Chemical Communications, 2002 , # 17 p. 1908 - 1909

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Citation Number: 2

Abstract

Quinone methides (QMs) are highly reactive intermediates, which may act either as electrophiles 1 or electron poor heterodienes. 2 In fact, QMs have been widely used in organic synthesis, in particular for carrying out 'reverse electron demand' Diels–Alder cycloadditions to give chroman derivatives. 3 It has been suggested that QM-like structures play a key role as intermediates in several biological processes, including enzyme inhibition 4 and DNA cross-linking. 5 ...

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