Enzymatic synthesis of carbon-fluorine bonds

…, O Nashiru, C Mayer, D Stoll, DL Jakeman…

Index: Zechel; Reid; Nashiru; Mayer; Stoll; Jakeman; Warren; Withers Journal of the American Chemical Society, 2001 , vol. 123, # 18 p. 4350 - 4351

Full Text: HTML

Citation Number: 52

Abstract

Halogenated secondary metabolites are ubiquitous in Nature. Over 3000 natural products containing chlorine, bromine, or iodine have been characterized to date, and scores are added to the list each year. 1 There is, however, a notable scarcity of fluorinated natural products, of which only 13 are known. 2 This may in part stem from the limited bioavailability of fluoride, which exists primarily in insoluble mineral forms. 3, 4 Equally elusive is an ...

Related Articles:

Major Change in Regiospecificity for the Exo-1, 3-β-glucanase from Candida albicans following Its Conversion to a Glycosynthase

[Wei, Jinhua; Lv, Xun; Lue, Yang; Yang, Gangzhu; Fu, Lifeng; Yang, Liu; Wang, Jianjun; Gao, Jianhui; Cheng, Shuihong; Duan, Qian; Jin, Cheng; Li, Xuebing European Journal of Organic Chemistry, 2013 , # 12 p. 2414 - 2419]

Modification at c-6 of unprotected glucopyranosyl fluoride using 6-Bromo-6-deoxy-α-d-glucopyranosyl Fluoride as the key compound.

[Horneman, Anne Marie; Lundt, Inge Journal of Carbohydrate Chemistry, 1995 , vol. 14, # 1 p. 1 - 8]

More Articles...