Acylation of amines with 5-phenyltetrazol-2-ylacetyl chloride

…, VY Zubarev, VS Poplavskii, VA Ostrovskii

Index: Putis; Zubarev; Poplavskii; Ostrovskii Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 7 p. 854 - 861

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Citation Number: 4

Abstract

The acylation of primary and secondary amines by 5-phenyltetrazol-2-ylacetyl chloride leads to the corresponding tetrazolylacetamides irrespective of the nature of the substituent in the structure of the amine. ... Keywords: 5-phenyltetrazol-2-ylacetamide, 5-phenyltetrazol-2-ylacetyl chloride, acylation. ... Tetrazolylacetic acids and their derivatives are regarded as potential biologically active compounds. A special position is occupied by the amides of tetrazolylacetic acids, ...

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