A structure-affinity relationship study on derivatives of N-[2-[4-(4-chlorophenyl) piperazin-1-yl] ethyl]-3-methoxybenzamide, a high-affinity and selective D4 receptor …

R Perrone, F Berardi, NA Colabufo…

Index: Journal of Medicinal Chemistry, , vol. 43, # 2 p. 270 - 277

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Citation Number: 29

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. The final step for the preparation of compounds 28, 29, 31, 36, 37, 40, and 41 was the alkylation of 1-(4-chlorophenyl) piperazine (14) with the appropriate alkyl halides (Scheme ...

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