One-step synthesis of pyridines and dihydropyridines in a continuous flow microwave reactor

…, RL Jenkins, MC Lubinu, C Mason

Index: Bagley, Mark C.; Fusillo, Vincenzo; Jenkins, Robert L.; Lubinu, M. Caterina; Mason, Christopher Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 1957 - 1968

Full Text: HTML

Citation Number: 13

Abstract

Abstract The Bohlmann–Rahtz pyridine synthesis and the Hantzsch dihydropyridine synthesis can be carried out in a microwave flow reactor or using a conductive heating flow platform for the continuous processing of material. In the Bohlmann–Rahtz reaction, the use of a Brønsted acid catalyst allows Michael addition and cyclodehydration to be carried out in a single step without isolation of intermediates to give the corresponding trisubstituted ...

Related Articles:

Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide

[Bagley, Mark C.; Glover, Christian Molecules, 2010 , vol. 15, # 5 p. 3211 - 3227]

A highly efficient regioselective one-pot synthesis of 2, 3, 6-trisubstituted pyridines and 2, 7, 7-trisubstituted tetrahydroquinolin-5-ones using K 5 CoW 12 O 40· 3H 2 O …

[Kantevari, Srinivas; Chary, Mahankhali Venu; Vuppalapati, Srinivasu V.N. Tetrahedron, 2007 , vol. 63, # 52 p. 13024 - 13031]

One-pot synthesis of pyridines or pyrimidines by tandem oxidation-heteroannulation of propargylic alcohols

[Bagley, Mark C.; Hughes, David D.; Sabo, Halima M.; Taylor, Paul H.; Xiong, Xin Synlett, 2003 , # 10 p. 1443 - 1446]

Carbon transfer reactions of functionalized oxazolidines and their open chain enamine tautomers to enamine nucleophiles. A facile synthesis of substituted pyridines …

[Singh, Kamaljit; Singh, Jasbir; Singh, Harjit Tetrahedron, 1998 , vol. 54, # 5-6 p. 935 - 942]

New N-halosuccinimide-mediated reactions for the synthesis of pyridines

[Synlett, , # 5 p. 811 - 814]

More Articles...