Integrated and passive 1, 2, 3-triazolyl groups in fluorescent indicators for Zinc (II) ions: thermodynamic and kinetic evaluations

…, RJ Clark, CW Levenson, MW Davidson, L Zhu

Index: Simmons, J. Tyler; Allen, John R.; Morris, Deborah R.; Clark, Ronald J.; Levenson, Cathy W.; Davidson, Michael W.; Zhu, Lei Inorganic Chemistry, 2013 , vol. 52, # 10 p. 5838 - 5850

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Citation Number: 41

Abstract

The thermodynamic and kinetic benefits of 1, 2, 3-triazolyl coordination in a multidentate ligand context are quantified via comparison of the properties of two isomeric ligands with integrated (coordinating) and passively (noncoordinating) attached 1, 2, 3-triazolyl groups, respectively. The 7-methoxycoumarin-containing ligand of the integrated design is an effective fluorescent indicator in imaging Zn ions in mammalian cells and rat hippocampal ...

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