Formate dehydrogenase-a biocatalyst with novel applications in organic chemistry

P Fröhlich, K Albert, M Bertau

Index: Froehlich, Peter; Albert, Kristin; Bertau, Martin Organic and Biomolecular Chemistry, 2011 , vol. 9, # 22 p. 7941 - 7950

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Citation Number: 12

Abstract

In the field of industrial biocatalysis, formate dehydrogenase (FDH) is well established, in particular for its broad application in cofactor regeneration. Further applications have been limited by the enzyme's narrow range of substrates. These restrictions have been overcome now by the finding, that the enzyme is capable of selectively cleaving formic acid esters to the respective alcohol. Five homologous alkyl formates and phenyl formate as an aromatic ...