1, 2, 3, 4-Tetrahydro-8-hydroxyquinoline-promoted copper-catalyzed coupling of nitrogen nucleophiles and aryl bromides

H Wang, Y Li, F Sun, Y Feng, K Jin…

Index: Wang, Huifeng; Li, Yaming; Sun, Fangfang; Feng, Yang; Jin, Kun; Wang, Xiuna Journal of Organic Chemistry, 2008 , vol. 73, # 21 p. 8639 - 8642

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Citation Number: 56

Abstract

Based on the dramatic accelerating effect of 2-aminophenol, three ligands derived from 2- aminophenol were developed. Copper-catalyzed coupling reaction of nitrogen-containing nucleophiles with aryl bromides was efficiently carried out under mild conditions using 1, 2, 3, 4-tetrahydro-8-hydroxyquinoline as a novel, simple, and versatile ligand.

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