The Journal of Organic Chemistry

Total syntheses of yohimbe alkaloids, with stereoselection for the normal, allo, and 3-epiallo series, based on annelations of 4-methoxy-1, 2-dihydropyridones

ME Kuehne, RS Muth

Index: Kuehne, Martin E.; Muth, Randy S. Journal of Organic Chemistry, 1991 , vol. 56, # 8 p. 2701 - 2712

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Citation Number: 61

Abstract

Background Starting with the synthesis of yohimbone by Swan in 1950,'synthetic studies directed at the Yohimbe alkaloids have provided a variety of approaches that, apart from their specific goals, advanced organic chemistry through the development of important synthetic methodologies. While a complete review of those syntheses is beyond the scope of this paper (and already available): we summarize here, for comparison, only the most ...

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